design
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علوم وتكنولوجيا
Ultrahighthroughput mapping of genetic design space
de Boer, C. G. et al. Deciphering eukaryotic gene-regulatory logic with 100 million random promoters. Nat. Biotechnol. 38, 56–65 (2020).…
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علوم وتكنولوجيا
Surface optimization governs local design of physical networks
Shapson-Coe, A. et al. A petavoxel fragment of human cerebral cortex reconstructed at nanoscale resolution. Science 384, eadk4858 (2024). Article …
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علوم وتكنولوجيا
Computational enzyme design by catalytic motif scaffolding
Cloning, protein production and purification RAD and MBH genes were obtained from IDT and GenScript, respectively (sequences can be found…
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علوم وتكنولوجيا
Computational design of metallohydrolases | Nature
Metallohydrolases catalyse some of the most difficult hydrolysis reactions in biology by using their bound metal ions to activate a…
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علوم وتكنولوجيا
A chaotic mix of brilliant cameras and baffling design choices
Smartphones are more than the sum of their parts, or at least, the best ones are. The Realme GT 8…
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علوم وتكنولوجيا
Semantic design of functional de novo genes from a genomic language model
Evo 1.5 pretraining Evo 1.5 was generated by extending the pretraining of the Evo 1 model, originally trained at a sequence context…
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علوم وتكنولوجيا
Atomically accurate de novo design of antibodies with RFdiffusion
Wilson, P. C. & Andrews, S. F. Tools to therapeutically harness the human antibody response. Nat. Rev. Immunol. 12, 709–719…
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علوم وتكنولوجيا
Design taken seriously, with few compromises
Pay attention to the name, as I’ve been using the Apple iPhone Air, not the iPhone 17 Air. That’s right,…
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علوم وتكنولوجيا
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Magnus, C. J. et al. Ultrapotent chemogenetics for research and potential clinical applications. Science 364, eaav5282 (2019). Article ADS CAS …
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