Two residues reprogram immunity receptors for nitrogen
Bozsoki, Z. et al. Ligand-recognizing motifs in plant LysM receptors are major determinants of specificity. Science 369, 663–670 (2020).
Google Scholar
Lemmon, M. A. & Schlessinger, J. Cell signaling by receptor tyrosine kinases. Cell 141, 1117–1134 (2010).
Google Scholar
Shiu, S. H. & Bleecker, A. B. Receptor-like kinases from Arabidopsisform a monophyletic gene family related to animal receptor kinases. Proc. Natl Acad. Sci. USA 98, 10763–10768 (2001).
Google Scholar
Zipfel, C. & Oldroyd, G. E. Plant signalling in symbiosis and immunity. Nature 543, 328–336 (2017).
Google Scholar
Ngou, B. P. M., Wyler, M., Schmid, M. W., Kadota, Y. & Shirasu, K. Evolutionary trajectory of pattern recognition receptors in plants. Nat. Commun. 15, 308 (2024).
Google Scholar
Johnson, J. L. et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature 613, 759–766 (2023).
Google Scholar
Ma, Y. et al. Comparisons of two receptor–MAPK pathways in a single cell-type reveal mechanisms of signalling specificity. Nat. Plants 10, 1343–1362 (2024).
Google Scholar
Bozsoki, Z. et al. Receptor-mediated chitin perception in legume roots is functionally separable from Nod factor perception. Proc. Natl Acad. Sci. USA 114, E8118–E8127 (2017).
Google Scholar
Miya, A. et al. CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis. Proc. Natl Acad. Sci. USA 104, 19613–19618 (2007).
Google Scholar
Wang, G. et al. Release of a ubiquitin brake activates OsCERK1-triggered immunity in rice. Nature 629, 1158–1164 (2024).
Google Scholar
Zhang, X. W. et al. The receptor kinase CERK1 has dual functions in symbiosis and immunity signalling. Plant J. 81, 258–267 (2015).
Google Scholar
Zhang, J. et al. A receptor required for chitin perception facilitates arbuscular mycorrhizal associations and distinguishes root symbiosis from immunity. Curr. Biol. 34, 1705–1717 (2024).
Google Scholar
Han, R. C. et al. Wild species rice OsCERK1DY-mediated arbuscular mycorrhiza symbiosis boosts yield and nutrient use efficiency in rice breeding. Mol. Breed. 44, 22 (2024).
Google Scholar
Miyata, K., et al. OsCERK2/OsRLK10, a homolog of OsCERK1, has a potential role for chitin-triggered immunity and arbuscular mycorrhizal symbiosis in rice. Plant Biotechnol. 39, 119–128 (2022).
Google Scholar
Feng, F. et al. A combination of chitooligosaccharide and lipochitooligosaccharide recognition promotes arbuscular mycorrhizal associations in Medicago truncatula. Nat. Commun. 10, 5047 (2019).
Google Scholar
Liao, D. H., Sun, X., Wang, N., Song, F. M. & Liang, Y. Tomato LysM receptor-like kinase SlLYK12 is involved in arbuscular mycorrhizal symbiosis. Front. Plant. Sci. 9, 1004 (2018).
Google Scholar
Limpens, E. et al. LysM domain receptor kinases regulating rhizobial Nod factor-induced infection. Science 302, 630–633 (2003).
Google Scholar
Radutoiu, S. et al. Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases. Nature 425, 585–592 (2003).
Google Scholar
Frank, M. et al. Single-cell analysis identifies genes facilitating rhizobium infection in Lotus japonicus. Nat. Commun. 14, 7171 (2023).
Google Scholar
Red Brewer, M. et al. The juxtamembrane region of the EGF receptor functions as an activation domain. Mol. Cell 34, 641–651 (2009).
Google Scholar
Zhou, Q. et al. The juxtamembrane domains of CERK1, BAK1, and FLS2 play a conserved role in chitin-induced signaling. J. Integr. Plant Biol. 62, 556–562 (2020).
Google Scholar
Schauser, L., Roussis, A., Stiller, J. & Stougaard, J. A plant regulator controlling development of symbiotic root nodules. Nature 402, 191–195 (1999).
Google Scholar
Rübsam, H. et al. Nanobody-driven signaling reveals the core receptor complex in root nodule symbiosis. Science 379, 272–277 (2023).
Google Scholar
Buendia, L., Girardin, A., Wang, T., Cottret, L. & Lefebvre, B. LysM receptor-like kinase and LysM receptor-like protein families: an update on phylogeny and functional characterization. Front. Plant Sci. 9, 1531 (2018).
Google Scholar
Rutten, L. et al. Duplication of symbiotic lysin motif receptors predates the evolution of nitrogen–fixing nodule symbiosis. Plant Physiol. 184, 1004–1023 (2020).
Google Scholar
Miyata, K. et al. The bifunctional plant receptor, OsCERK1, regulates both chitin-triggered immunity and arbuscular mycorrhizal symbiosis in rice. Plant Cell Physiol. 55, 1864–1872 (2014).
Google Scholar
Li, X. et al. Atypical receptor kinase RINRK1 required for rhizobial infection but not nodule development in Lotus japonicus. Plant Physiol. 181, 804–816 (2019).
Google Scholar
Liu, M., Soyano, T., Yano, K., Hayashi, M. & Kawaguchi, M. ERN1 and CYCLOPS coordinately activate NIN signaling to promote infection thread formation in Lotus japonicus. J. Plant Res. 132, 641–653 (2019).
Google Scholar
Schiessl, K., et al. NODULE INCEPTION recruits the lateral root developmental program for symbiotic nodule organogenesis in Medicago truncatula. Curr. Biol. 29, 3657–3668 (2019).
Google Scholar
Lee, T. et al. Light-sensitive short hypocotyl genes confer symbiotic nodule identity in the legume Medicago truncatula. Curr. Biol. 34, 825–840 (2024).
Google Scholar
Hohmann, U., Lau, K. & Hothorn, M. The structural basis of ligand perception and signal activation by receptor kinases. Annu. Rev. Plant Biol. 68, 109–137 (2017).
Google Scholar
Chiu, C. H. & Paszkowski, U. Receptor-like kinases sustain symbiotic scrutiny. Plant Physiol. 182, 1597–1612 (2020).
Google Scholar
Huse, M. & Kuriyan, J. The conformational plasticity of protein kinases. Cell 109, 275–282 (2002).
Google Scholar
Gust, A. A., Willmann, R., Desaki, Y., Grabherr, H. M. & Nürnberger, T. Plant LysM proteins: modules mediating symbiosis and immunity. Trends Plant Sci. 17, 495–502 (2012).
Google Scholar
Murakami, E. et al. Epidermal LysM receptor ensures robust symbiotic signalling in Lotus japonicus. eLife 7, e33506 (2018).
Google Scholar
Nguyen, T. V. et al. An assemblage of Frankia Cluster II strains from California contains the canonical nodgenes and also the sulfotransferase gene nodH. BMC Genomics 17, 796 (2016).
Google Scholar
Griesmann, M. et al. Phylogenomics reveals multiple losses of nitrogen–fixing root nodule symbiosis. Science 361, eaat1743 (2018).
Google Scholar
Mudumbi, K. C. et al. Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes. Cell Rep. 43, 113603 (2024).
Google Scholar
Sheetz, J. B., Lemmon, M. A. & Tsutsui, Y. Dynamics of protein kinases and pseudokinases by HDX-MS. Methods Enzymol. 667, 303–338 (2022).
Google Scholar
Jhu, M. Y. & Oldroyd, G. E. D. Dancing to a different tune, can we switch from chemical to biological nitrogen fixation for sustainable food security? PLoS Biol. 21, e3001982 (2023).
Google Scholar
Malolepszy, A. et al. A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis. eLife 7, e38874 (2018).
Google Scholar
Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. Basic local alignment search tool. J. Mol. Biol. 215, 403–410 (1990).
Google Scholar
Márquez, A. J. Lotus japonicus Handbook (Springer, 2005).
Weber, E., Engler, C., Gruetzner, R., Werner, S. & Marillonnet, S. A modular cloning system for standardized assembly of multigene constructs. PLoS ONE 6, e16765 (2011).
Google Scholar
Handberg, K. & Stougaard, J. Lotus japonicus, an autogamous, diploid legume species for classical and molecular genetics. Plant J. 2, 487–496 (1992).
Google Scholar
Zhukov, V. et al. The pea Sym37receptor kinase gene controls infection-thread initiation and nodule development. Mol. Plant Microbe Interact. 21, 1600–1608 (2008).
Google Scholar
Maekawa, T. et al. Gibberellin controls the nodulation signaling pathway in Lotus japonicus. Plant J. 58, 183–194 (2009).
Google Scholar
Kelly, S. J. et al. Conditional requirement for exopolysaccharide in the Mesorhizobium–Lotus symbiosis. Mol. Plant Microbe Interact. 26, 319–329 (2013).
Google Scholar
Hansen, S. B. et al. A conserved juxtamembrane motif in plant NFR5 receptors is essential for root nodule symbiosis. Proc. Natl Acad. Sci. USA 121, e2405671121 (2024).
Google Scholar
Schindelin, J. et al. Fiji: an open-source platform for biological-image analysis. Nat. Methods 9, 676–682 (2012).
Google Scholar
Villanueva, R. A. M. & Chen, Z. J. ggplot2: elegant graphics for data analysis (2nd ed.). Meas. Interdiscip. Res. 17, 160–167 (2019).
Kruskal, W. H. & Wallis, W. A. Use of ranks in one-criterion variance analysis. J. Am. Stat. Assoc. 47, 583–621 (1952).
Google Scholar
Dunn, O. J. Multiple comparisons using rank sums. Technometrics 6, 241–252 (1964).
Google Scholar
Girden, E. ANOVA (Sage Publications, 1992).
Tukey, J. W. Comparing individual means in the analysis of variance. Biometrics 5, 99–114 (1949).
Google Scholar
Cianci, M. et al. P13, the EMBL macromolecular crystallography beamline at the low-emittance PETRA III ring for high- and low-energy phasing with variable beam focusing. J. Synchrotron Radiat. 24, 323–332 (2017).
Google Scholar
Brehm, W., Triviño, J., Krahn, J. M., Usón, I. & Diederichs, K. XDSGUI: a graphical user interface for XDS, SHELX and ARCIMBOLDO. J. Appl. Crystallogr. 56, 1585–1594 (2023).
Google Scholar
Mccoy, A. J. et al. Phaser crystallographic software. J. Appl. Crystallogr. 40, 658–674 (2007).
Google Scholar
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D 66, 213–221 (2010).
Google Scholar
Emsley, P., Lohkamp, B., Scott, W. G. & Cowtan, K. Features and development of Coot. Acta Crystallogr. D 66, 486–501 (2010).
Google Scholar
The PyMOL Molecular Graphics System v.1.8 (Schrödinger, 2015).
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